Publications

Mailer RK, Allende M, Heestermans M, Schweizer M, Deppermann C, Frye M, Pula G, Odeberg J, Gelderblom M, Rose-John S, Sickmann A, Blankenberg S, Huber T, Kubisch C, Maas C, Gambaryan S, Firsov S, Stavrou EX, Butler L and Renné T. Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate. Blood (2020) accepted manuscript

Martinod K and Deppermann C. Immunothrombosis and thromboinflammation in host defense and disease. Platelets (2020) accepted manuscript

Deppermann C*, Peiseler M*, Zindel J, Zbytnuik L, Lee WY, Pasini E, Baciu C, Matelski J, Lee Y, Kumar D, Humar A, Surewaard B, Kubes P and Bhat M. Tacrolimus impairs Kupffer cell capacity to control bacteremia: why transplant recipients are susceptible to infection. Hepatology (2020) https://doi.org/10.1002/hep.31499 *equal contribution

Deppermann C, Kratofil RM, Peiseler M, David BA, Zindel J, Castanheira FVES, van der Wal F, Carestia A, Jenne CN, Marth JD and Kubes P. Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets. J. Exp. Med. 217(4): e20190723 (2020) https://doi.org/10.1084/jem.20190723

Jorch SK, Surewaard BGJ, Hossain M, Peiseler M, Deppermann C, Deng J, Bogoslowski A, van der Wal F, Omri A, Hickey MJ and Kubes P. GATA6+ macrophages in the peritoneum function as a portal for Staphylococcus aureus dissemination. J. Clin. Invest. 129(11): 4643-56 (2019) https://doi.org/10.1172/JCI127286

Deniset JF, Belke D, Lee W-Y, Jorch SK, Deppermann C, Hassanabad AF, Turnbull JD, Teng G, Rozich I, Hudspeth K, Kanno Y, Brooks SR, Hadjantonakis A-K, O’Shea JJ, Weber GF, Fedak PWM and Kubes P. Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis. Immunity 51: 131-40 (2019) https://doi.org/10.1016/j.immuni.2019.06.010

Malehmir M, Pfister D, Gallage S, Szydlowska M, Inverso D, Kotsiliti E, Leone V, Peiseler M, Surewaard B, Rath D, Ali S, Wolf M, Drescher H, Healy M, Dauch D, Kroy D, Krenkel O, Kohlhepp M, Engleitner T, Olkus A, Sijmonsma T, Volz J, Deppermann C, Stegner D, Helbling P, Nombela-Arrieta C, Rafiei A, Hinterleitner M, Rall M, Baku F, Borst O, Wilson CL, Leslie J, O’Connor T, Weston CJ, Adams DH, Sheriff L, Teijeiro A, Prinz M, Bogeska R, Anstee N, Bongers MN, Notohamiprodjo M, Geisler T, Withers DJ, Ware J, Mann DA, Augustin HG, Vegiopoulos A, Milsom MD, Rose AJ, Lalor PF, Llovet JM, Pinyol R, Tacke F, Rad R, Matter M, Djouder N, Kubes P, Knolle PA, Unger K, Zender L, Nieswandt B, Gawaz M, Weber A and Heikenwälder M. Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer. Nat. Medicine 25(4): 641-55 (2019) https://doi.org/10.1038/s41591-019-0379-5

Gotru SK, van Geffen JP, Nagy M, Mammadova-Bach E, Eilenberger J, Volz J, Manukjan G, Schulze H, Wagner L, Eber S, Schambeck C, Deppermann C, Brouns S, Nurden P, Greinacher A, Sachs U, Nieswandt B, Hermanns HM, Heemskerk JWM and Braun A. Defective Zn2+ homeostasis in mouse and human platelets with α- and δ-storage pool diseases. Sci. Rep. 9(1): 8333 (2019) https://doi.org/10.1038/s41598-019-44751-w

Surewaard BGJ, Thanabalasuriar A, Zeng Z, Tkaczyk C, Cohen TS, Bardoel BW, Jorch SK, Deppermann C, Bubeck Wardenburg J, Davis RP, Jenne CN, Stover KC, Sellman BR and Kubes P. α-Toxin Induces Platelet Aggregation and Liver Injury during Staphylococcus aureus Sepsis. Cell Host Microbe 24(2): 271-84 (2018) https://doi.org/10.1016/j.chom.2018.06.017

Deppermann C and Kubes P. Start a fire, kill the bug: The role of platelets in inflammation and infection. Innate Immun. 24(6): 335-48 (2018) https://doi.org/10.1177/1753425918789255

Deppermann C. Platelets and vascular integrity. Platelets 29(6): 549-55 (2018) https://doi.org/10.1080/09537104.2018.1428739

Drube S, Grimlowski R, Deppermann C, Fröbel J, Kraft F, Andreas N, Stegner D, Dudeck J, Weber F, Rödiger M, Göpfert C, Drube J, Reich D, Nieswandt B, Dudeck A and Kamradt T. The Neurobeachin-like 2 protein (Nbeal2) regulates mast cell homeostasis. J. Immunol. 199(8): 2948-57 (2017) https://doi.org/10.4049/jimmunol.1700556

Deppermann C, Kraft P, Volz J, Schuhmann MK, Beck S, Wolf K, Stegner D, Stoll G and Nieswandt B. Platelet secretion is crucial to prevent bleeding in the ischemic brain but not in the inflamed skin or lung in mice. Blood 129(12): 1702-07 (2017) https://doi.org/10.1182/blood-2016-12-750711

Pachel C, Mathes D, Arias-Loza A-P, Heitzmann W, Nordbeck P, Deppermann C, Lorenz V, Hofmann U, Nieswandt B and Frantz S. Inhibition of platelet GPVI protects against myocardial ischemia-reperfusion injury. Arterioscler. Thromb. Vasc. Biol. 36(4): 629-35 (2016) https://doi.org/10.1161/atvbaha.115.305873

Deppermann C and Kubes P. Platelets and infection. Semin. Immunol. 28(6): 536-45 (2016) https://doi.org/10.1016/j.smim.2016.10.005

Lowe KL, Finney BA, Deppermann C, Hagerling R, Gazit SL, Frampton J, Buckley CD, Camerer E, Nieswandt B, Kiefer F and Watson SP. Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development. Blood 125(24): 3769-77 (2015) https://doi.org/10.1182/blood-2014-09-603803

Kraft P, Göb E, Schuhmann MK, Göbel K, Deppermann C, Thielmann I, Herrmann AM, Lorenz K, Brede M, Stoll G, Meuth SG, Nieswandt B, Pfeilschifter W and Kleinschnitz C. FTY720 ameliorates acute ischemic stroke in mice by reducing thrombo-inflammation but not by direct neuroprotection. Stroke 44(11): 3202-10 (2013) https://doi.org/10.1161/strokeaha.113.002880

Stegner D*, Deppermann C*, Kraft P, Morowski M, Kleinschnitz C, Stoll G and Nieswandt B. Munc13-4 mediated secretion is essential for infarct progression but not intracranial haemostasis in acute stroke. J. Thromb. Haemost. 11(7): 1430-33 (2013) *equal contribution https://doi.org/10.1111/jth.12293

Deppermann C, Nurden P, Nurden AT, Nieswandt B and Stegner D. The Nbeal2-/- mouse as a model for the gray platelet syndrome. Rare Dis. 1 (1) e26561 (2013) https://doi.org/10.4161/rdis.26561

Deppermann C, Cherpokova D, Nurden P, Schulz JN, Thielmann I, Kraft P, Vögtle T, Kleinschnitz C, Dütting S, Krohne G, Eming S, Nurden A, Eckes B, Stoll G, Stegner D and Nieswandt B. Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice. J. Clin. Invest. 123(8): 3331-42 (2013) https://doi.org/10.1172/JCI69210


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